Thursday 18 July 2019

Huntington's disease: Could a cancer drug hold the key?

Huntington's disease: Could a cancer drug hold the key?

Medication which is used to treat cancer could potentially be an effective therapy for Huntington's disease, according to new research led by Duke University School of Medicine in Durham, NC. Even the drug may also offer a pathway to treat other neurodegenerative diseases.

Huntington's disease is an inherited disorder that may also leads to the degeneration of certain nerve cells in the brain. The condition is progressive and affects movement, cognition, and behavior.

There is no cure, no therapies for Huntington's disease to stop or slow down its progression. People with Huntington's often die within 15 to 20 years of being affected by diagnosed.

Previous researchers found that a compound known as KD3010, tested in the treatment of diabetes, was effective in reducing disease progression and overall neurodegeneration and improving motor function.

The new study explores about treating mice with the equivalent of Huntington's disease with bexarotene, a cancer treatment for advanced skin lymphomas.

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