Saturday, 27 October 2018

Scientific Journal of Sports Medicine, Rehabilitation and Research


Endurance Work Capacity of Children is Related to Cardiac Function, But the Trainability is Associated with Angiotensin-Converting Enzyme Genotype

Gen-Hai Zhu*, Xin-Hui Fu, Fu-Jin Liu, Chun-Ying Chen, Hai-Yan Huang, Lan Hong, Kang Wang, Sheng-Tan Wang and Lang Zheng


Abstract:

Objective: The objective of this study was to investigate the safety margin of ovary-sparing local tumorectomy by detecting the expression of CK-7, CA125 and survivin in paraneoplastic tissues at different distances from orthotopic human epithelial ovarian carcinomas in nude mice. 
Methods: RT-PCR and IHC were used to measure the expression levels of CK-7, CA125 and survivin in the ovarian tissues of 20 normal nude mice as well as in the cancer tissue and paraneoplastic tissues (respectively 1 mm - 1.5 mm, 1.5 mm – 3 mm, 3 mm - 4.5 mm from the cancer) of 18 nude mice with orthotopic human epithelial ovarian carcinomas. 
Results: According to the RT-PCR and IHC results, the expression levels or positive rates of CK-7, CA125 and survivin in the ovarian tissue 1 mm - 1.5 mm from the cancer were significantly higher than those in the normal tissue (P<0.01), but slightly lower than those in the cancer tissue with no statistical difference (P>0.05); the expression levels or positive rates in the ovarian tissue 1.5 mm – 3 mm from the cancer were significantly lower than those in the cancer tissue (P<0.01), but slightly higher than those in the normal tissue with no statistical difference (P>0.05); the expression levels or positive rates in the ovarian tissue 3 mm - 4.5 mm from the cancer were significantly higher than those in the normal tissue (P<0.01), but slightly lower than those in the cancer tissue with no statistical difference (P>0.05); there were no statistically significant differences in the expression levels or positive rates between the ovarian tissue 3 mm - 4.5 mm from the cancer and the normal ovarian tissue (P>0.05). 
Conclusions: The expression levels or positive rates of CK-7, CA125 and survivin in the paraneoplastic tissues showed a decreasing trend towards the non-cancer side; the tissue 1 mm - 1.5 mm from the cancer may be an area with a risk of occult metastasis and 3 mm is the minimum safe distance for performing ovary-sparing local tumorectomy for orthotopic human epithelial ovarian carcinomas in nude mice.



Monday, 8 October 2018

Scientific Journal of Sports Medicine, Rehabilitation and Research

Skateboarding-related Injuries Among Males 35-55 Years Old in the US

Ches Jones

Skateboarding is a popular activity among teenagers and young adults. However, the activity has been increasing in popularity among older adults the past 10 years. Injuries from skateboarding among older males have not been reported in the literature. The purpose of this study was to review emergency room reports documented in the National Electronic Injury Surveillance System for skateboarding injuries among males 35-55 from 2000-2009. An estimated total of 29,450 reports were documents in NEISS. A majority of the injuries occurred to males 35-40 (55%), who were white (72%). The most common locations for the injury were the home, street, and place of recreation. The most common body regions injured were the hand, arm, and upper trunk. 

The head region was noted in 15% of reports. The most common diagnoses were fractures (40%) and soft tissue injuries (36%). Results noted that fractures are a concern for this age group as well as the number of injuries affecting the head region. While it is not known the skateboarding skill level of the injured, older participants should receive proper education and training before participating in an activity that has a high potential for injury. As the rate for participation in skateboarding increases for older adults, so should the concern for serious injury. Retail stores specializing in skateboards should consider offering trainings and advice on the activity for enthusiasts who lack sufficient skateboarding skills.

Vivid Journal of Dental Sciences

Occlusal Disease

Kengo Torii*

This is the review of our practice for temporomandibular disorders. Some current articles have concluded that the available evidence does not support occlusal adjustment as a reasonable therapy for temporomandibular disorders. However, occlusal adjustments in previous studies were used the centric relation (retruded contact position) as a reference position. Therefore, the treatment outcome of occlusal adjustment using the bite plate-induced occlusal position as a muscular reference position to make coincident with habitual occlusal position was reviewed.

Lifestyle is a threat to gut bacteria: Ötzi proves it, study shows

The intestinal microbiome is a delicate ecosystem made up of billions and billions of microorganisms, bacteria in particular, that support ...